Prof. Dr. med. Stephan Rohr
34 Original Articles
sorted by year and first author
| S. Morel, Frias M.A., Rosker Ch., James R.W., Rohr S., Kwak B.R.. The natural cardioprotective particle HDL modulates connexin43 gap junction channels. Cardiovasc. Res. 93:41-49, 2012 DOI |
| S. Rohr, Arrhythmogenic Implications of Fibroblast-Myocyte Interactions. . Circ. Arrhythm. Electrophysiol. 5:442-452, 2012 DOI |
| M. Miragoli, Siti H., Kadir S. A., Sheppard M. N., Salvarani N., Virta M., Wells S., Lab M.J., Nikolaev V.O., Moshkov A., Hague W.M., Rohr S., Williamson C., Gorelik J.. A protective antiarrhythmic role of ursodeoxycholic acid in an InVitro rat model of the cholestatic fetal heart. HEPATOLOGY 54:1282-1292, 2011 DOI |
| S. Rohr. Cardiac fibroblasts in cell culture systems: Myofibroblasts all along?. J Cardiovasc Pharmacol 57:389-399, 2011 |
| C. Rosker, N. Salvarani, S. Schmutz, T. Grand, S. Rohr. Abolishing myofibroblast arrhythmogeneicity by pharmacological ablation of a-smooth muscle actin containing stress fibers. Circ. Res. 109:1120-1131, 2011 |
| M Moridi, S. Tanner, N. Wyrsch, P.A. Farine, S. Rohr. A highly sensitive a-Si photodetector array with integrated filter for optical detection in MEMS. Procedia Chemistry 1:1367-1370, 2009 DOI |
| M. Helfenstein, M. Miragoli, S. Rohr, L. Mü, P. Wick, M. Mohr, P. Gehr, B. Rothen-Rutishauser. Effects of combustion-derived ultrafine particles and manufactured nanoparticles on heart cells in vitro. Toxicology 253:70-78, 2008 (Elsevier) DOI |
| A.A Kondratyev, J.G.C. Ponard, A. Munteanu, S. Rohr, J.P. Kucera. Dynamic changes of cardiac conduction during rapid pacing. Am. J. Physiol. 292: H1796-H1811, 2007 |
| M. Miragoli, N. Salvarani, S. Rohr. Myofibroblasts induce ectopic activity in cardiac tissue. Circ. Res. 101:755-758, 2007 |
| V. Muñoz, K.R. Grzeda, T. Desplantez, S.V. Pandit, S. Mironov, S.M. Taffet, S. Rohr, A.G. Kléber, J. Jalife. Adenoviral expression of IKs contributes to wavebreak and fibrillatory conduction in neonatal rat ventricular cardiomyocyte monolayers. Circ. Res. 101:475-483, 2007 |
| S. Rohr. Molecular crosstalk between mechanical and electrical junctions at the intercalated disc. Circ. Res. 101:637-639 , 2007 |
| M. Miragoli, G. Gaudesius, S. Rohr. Electrotonic modulation of cardiac impulse conduction by myofibroblasts. Circ. Res. 98:801-810, 2006 |
| L. Berdondini, P.D. van der Wal, O. Guenat, N.F. de Rooij, M. Koudelka-Hep, P. Seitz, R. Kaufmann, P. Metzler, N. Blanc, S. Rohr. High-density electrode array for imaging in vitro electrophysiological activity. Biosens. Bioelectron. 21: 167-174, 2005 |
| G. Gaudesius, M. Miragoli, S.P. Thomas, S. Rohr. Coupling of Cardiac Electrical Activity Over Extended Distances by Fibroblasts of Cardiac Origin. Circ. Res. 93:421-428, 2003 |
| S. Rohr, R. Flückiger-Labrada, J.P. Kucera. Photolithographically defined deposition of attachment factors as a versatile method for patterning the growth of different cell types in culture. Pflugers Arch. 446:125-132, 2003 |
| J.P. Kucera, S. Rohr, Y. Rudy. Localization of sodium channels in intercalated disks modulates cardiac conduction. Circ. Res. 91, No 12, 1176-1182, 2002 |
| V.G. Fast, S. Rohr, R.E. Ideker. Nonlinear changes of transmembrane potential caused by defibrillation shocks in strands of cultured myocytes. Am. J. Physiol. 278:H688-H697, 2000 |
| A.M. Gillis, V.G. Fast, S. Rohr, A.G. Kléber. Mechanism of ventricular defibrillation. The role of tissue geometry in the changes in transmembrane potential in patterned myocyte cultures. Circulation 101:2438-2445, 2000 |
| J.P. Kucera, M.O. Heuschkel, P. Renaud, S. Rohr. Power-law behavior of beat-rate variability in monolayer cultures of neonatal rat ventricular myocytes. Circ. Res. 86:1140-1145, 2000 |
| V.G. Fast, S. Rohr, A.M. Gillis, A.G. Kléber. Activation of cardiac tissue by extracellular electrical shocks: Formation of ’secondary sources’ at intercellular clefts in monolayers of cultured myocytes. Circ. Res. 82:375-385, 1998 |
| J.P. Kucera, A.G. Kléber, S. Rohr. Slow conduction in cardiac tissue, ii: Effects of branching tissue geometry. Circ. Res. 83:795-805, 1998 |
| S. Rohr, J.P. Kucera. Optical recording system based on a fiber optic image conduit: Assessement of microscopic activation patterns in cardiac tissue. Biophys. J. 75:1062-1075, 1998 |
| S. Rohr, J.P. Kucera, A.G. Kléber. Slow conduction in cardiac tissue, i: Effects of a reduction of excitability versus. A reduction of electrical coupling on microconduction. Circ. Res. 83:781-794, 1998 |
| S. Rohr, J.P. Kucera. Involvement of the calcium inward current in cardiac impulse propagation: Induction of unidirectional conduction block by nifedipine and reversal by bay k 8644. Biophys. J. 72:754-766, 1997 |
| S. Rohr, J.P. Kucera, V.G. Fast, A.G. Kléber. Paradoxical improvement of impulse conduction in cardiac tissue by partial cellular uncoupling. Science 275:841-844, 1997 |
| A.M. Gillis, V.G. Fast, S. Rohr, A.G. Kléber. Spatial changes in transmembrane potential during extracellular electrical shocks in cultured monolayers of neonatal rat ventricular myocytes. Circ. Res. 79:676-690, 1996 |
| S. Rohr, B.M. Salzberg. Multiple site optical recording of transmembrane voltage in patterned growth heart cell cultures: Assessing electrical behavior, with microsecond resolution, on a cellular and subcellular scale. Biophys. J. 67:1301-1315, 1994 |
| S. Rohr, B.M. Salzberg. Characterization of impulse propagation at the microscopic level across geometrically defined expansions of excitable tissue: Multiple site optical recording of transmembrane voltage (msortv) in patterned growth heart cell cultures. J. Gen. Physiol. 104:287-309, 1994 |
| A.L. Obaid, D.J. Zou, S. Rohr, B.M. Salzberg. Optical recording with single cell resolution from a simple mammalian nervous system: Electrical activity in ganglia from the submucuous plexus of the guinea-pig ileum. Biol Bull Mar Biol Lab 183: 340-342, 1992 |
| S. Rohr, B.M. Salzberg. Discontinuities in action potential propagation along chains of single ventricular myocytes in culture: Multiple site optical recording of transmembrane voltage (msortv) suggests propagation delays at the junctional sites between cells. Biol Bull Mar Biol Lab 183:342-343, 1992 |
| S. Rohr, D.M. Schölly, A.G. Kléber. Patterned growth of neonatal rat heart cells in culture. Morphological and electrophysiological characterization. Circ. Res. 68:114-130, 1991 |
| S. Rohr. A computerized device for long term measurements of the contraction frequency of cultured rat heart cells under stable incubating conditions. Pflugers Arch. 416:201-206, 1990 |
| G. Schmilinsky, A. Rüdisüli, M Willi, S. Rohr, R. Weingart. Effects of arachidonic acid on gap junctions of neonatal rat heart cells. Pflugers Arch. 417:149-156, 1990 |
| A. Koch, S. Rohr, J. Plaschkes et al.. Incidence of gastroesophageal reflux following repair of esophageal atresia. Prog. Ped. Surg. 19:103-113, 1986 |
10 Reviews
sorted by year and first author
| S. Rohr. Cell to bedside: Myofibroblasts in diseased hearts: new players in cardiac arrhythmias?. Heart Rhythm 6:847-856, 2009 DOI |
| C. Rosker, N. Salvarani, S. Rohr. Reducing Myofibroblast Arrhythmogeneicity by Pharmacological Targeting of Their Cytoskeleton. Circulation 120:S635; Abstract 2424, 2009 |
| C. Rosker, N. Salvarani, S. Rohr. Modification of actin fibers changes the electrical phenotype of cardiac myofibroblasts. BMC Pharmacology 9(Suppl2):A15, 2009 |
| N Salvarani, C. Rosker, S. Rohr. Arrhythmogenic effects of transforming growth factor-β1 on hybrid cardiomyocyte-myofibroblast preparations. Circulation 120:S635; abstract 2427, 2009 |
| S. Rohr. Role of gap junctions in the propagation of the cardiac action potential. Cardiovasc. Res. 62: 309-322, 2004 |
| J.P. Kucera, A.G. Kléber, S. Rohr. Slow conduction in cardiac tissue: Insights from optical mapping at the cellular level. J. Electrocardiol. 34 suppl 1:57-64, 2001 |
| S. Rohr, A.G. Kléber, J.P. Kucera. Optical recording of impulse propagation in designer cultures. Cardiac tissue architectures inducing ultra-slow conduction. Trends in Cardiovasc Med 9:173-179, 1999 |
| S. Rohr, J.P. Kucera, A.G. Kléber. Form and function: Impulse propagation in designer cultures of cardiomyocytes. News Physiol Sci 12:171-177, 1997 |
| A.G. Kléber, V.G. Fast, J.P. Kucera, S. Rohr. Physiologie und Pathophysiologie der kardialen Erregungsleitung. Zeitschrift für Kardiologie 85:25-33, 1996 |
| S. Rohr. Determination of impulse conduction characteristics at a microscopic scale in patterned growth heart cell cultures using multiple site optical recording of transmembrane voltage. J. Cardiovasc. Electrophysiol. 6:551-568, 1995 |
9 Book Articles
sorted by year and first author
| S. Rohr, M. Miragoli. Cardiac electrophysiology: From cell to bedside. Cardiac myofibroblasts and arrhythmogenesis. In: Zipes DP, Jalife J, eds. 5th ed. Philadelphia:Saunders; 2009:269-278. 2009 |
| S. Rohr, M. Miragoli. Cardiac myofibroblasts and arrhythmogenesis. In: Zipes DP, Jalife J, eds. Cardiac electrophysiology: From cell to bedside.5th ed. Philadelphia: Saunders; 2008:269-278. 2008 |
| S. Rohr, J.P. Kucera. Cardiac tissue architecture determines velocity and safety of propagation. Cardiac Electrophysiology: From Cell To Bedside, 4th Edition 222 - 231, 2004 ( DP. Zipes, J. Jalife eds.) |
| S. Rohr. Optical mapping of microscopic impulse propagation. In:. Quantitative Cardiac Electrophysiology (Eds. C. Cabo, D.S. Rosenbaum) pp. 507-554, 2002 (Marcel Dekker Inc) |
| A.G. Kléber, S. Rohr, V.G. Fast. Role of cell-to-cell coupling, structural discontinuities, and tissue anisotropy in propagation of the electrical impulse. In: Opitcal Mapping of Cardiac Excitation and Arrhythmias (Eds. D.S. Rosenbaum, J. Jalife) Futura Pu 137-155, 2001 (Futura Publishing Co. Inc. Armonk, NY) |
| S. Rohr, J.P. Kucera. Optical mapping of impulse propagation between cardiomyocytes. In: Opitcal Mapping of Cardiac Excitation and Arrhythmias (Eds. D.S. Rosenbaum, J. Jalife) Futura Pu pp. 113-135, 2001 |
| A.G. Kléber, J.P. Kucera, S. Rohr. Principles of slow and discontinuous conduction. Experimental observations. In: Magalev T, Tchou JT, eds. Atrial av nodal electrophysiology: A view from the Millenium. Armonk, NY: Futura Publishing Co; 2000:73-88. 2000 |
| A.G. Kléber, V.G. Fast, S. Rohr. Continuous and discontinuous propagation. In: Zipes DG, Jalife J, eds. Cardiac electrophysiology: From cell to bedside. Philadelphia: W.B.Saunders; 1999:205-213. 1999 |
| A.G. Kléber, V.G. Fast, S. Rohr. Microscopic conduction in cell cultures assessed by high-resolution optical mapping and computer simulation. Armonk, NY: Futura Publishing Company, Inc. 1997 |
Abstracts
sorted by year and first author
| M Moridi, Tanner S, Farine P-A, Rohr S. Microfabricated biointerface for high density microelectrode arrays. Proc. of the 6th International Meeting on Substrate-Integrated Micro electrode Arrays (MEA), Reutlingen, Germany, July 8-11. 2008 |
| N Salvarani, Miragoi M, Rohr S. Effects of cytokines on electropphysiological properties of hybrid cardiomyocyte-myofibroblast preparations. Annual meeting of the Swiss Cardiovascular Research and Training Network, Bern. 2008 |
| M. Miragoli, Rohr S. Ectopic activity arising at borderzones between myofibroblasts and cardiom. Circulation 116:II_217:1085, 2007 |
| M. Miragoli, Rohr S. Myofibroblast induced ectopic activity in cardiac tissue. Gordon Research Conference on Cardiac Arrhythmia Mechanisms, Ventura Beach, CA, USA. 2007 |
